From Phthalate to Phthalate-4,5-cis-dihydrodiol

Graphic of the reaction.

Graphic of its mechanism.

Medline reference
Ballou D, Batie C. Prog Clin Biol Res (1988) 274: 211-26.

Search Medline for phthalate 4,5-dioxygenase AND bacteria.
39 citations on May 30, 2012. 
              Phthalate              
                  |
                  |  NADH + H+ + O2
        phthalate | /
  4,5-dioxygenase |/
        1.14.12.7 | Search GenBank, 255 hits on Apr. 03, 2012
            Kyoto |\
           ExPASy | \
                  |  NAD+
                  v
    Phthalate-4,5-cis-dihydrodiol
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-unsubstituted Aromatic -----> vic-Dihydrodihydroxyaromatic (bt0367)
[Phthalate Family] [BBD Main Menu]

Page Author(s): Derek Adams, Stephen Stephens and Meaghan Fitzgerald
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0102.
It was generated on November 14, 2025 at 2:10:01 PM CST. 

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