From 5,6-Dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline to 3-Methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon

Graphic of the reaction.

Medline reference
Schach S, Schwarz G, Fetzner S, Lingens F. Biol Chem Hoppe Seyler (1993) 374(3): 175-81.

Search Medline for 3-methylquinoline degradation.
3 citations on March 09, 2012. 
                            5,6-Dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline                            
                                                    |
                                                    |  O2
  5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline | /
                                        dioxygenase |/
                                          1.13.11.- |
                                                    |
                                             ExPASy |
                                                    |
                                                    v
                       3-Methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
5,6-Dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline derivative -----> 3-Methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon derivative (bt0281)
[3-Methylquinoline] [BBD Main Menu]

Page Author(s): Sandy Etienne
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0049.
It was generated on November 16, 2025 at 9:20:25 AM CST. 

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