From 2-Hydroxy-6-ketononatrienedioate to cis-2-Hydroxypenta-2,4-dienoate and Fumarate

Graphic of the reaction.

Medline reference

Chalabaev S, Turlin E, Bay S, Ganneau C, Brito-Fravallo E, Charles JF, Danchin A, Biville F. Appl Environ Microbiol (2008) 74(6): 1717-25.

Search Medline for cinnamic acid AND 3-phenylpropionate AND dioxygenase.

3 citations on March 09, 2012.

                          2-Hydroxy-6-ketononatrienedioate                           
                                          |
                                          |  OH-
  2-hydroxy-6-ketonona-2,4-dienedoic acid | /
                                hydrolase |/
                                 3.7.1.14 | Search GenBank, 33 hits on Apr. 03, 2012
                                    Kyoto |
                                   ExPASy |
                                          |
                                          v
                     cis-2-Hydroxypenta-2,4-dienoate + Fumarate                      

EAWAG-BBD Biotransformation rules in accord with this reaction:

1-Aldo/keto-2,4-diene-5-ol -----> Carboxylate + 1-ene-4-one (bt0040)

Page Author(s): Michael Turnbull
February 22, 2010 Contact Us

This is the EAWAG-BBD reaction, reacID# r1622.
It was generated on November 29, 2024 at 10:43:29 PM CST.

© 2024, EAWAG.