From 2,4,6-Trinitrotoluene to 4-Amino-2,6-dinitrotoluene

Graphic of the reaction.

Medline reference
Alvarez MA, Kitts CL, Botsford JL, Unkefer PJ. Can J Microbiol (1995) 41(11): 984-91.

Search Medline for trinitrotoluene AND nitroreductase.
40 citations on March 09, 2012. 

       2,4,6-Trinitrotoluene       
                 |
                 |  3NAD(P)H + 3H+
         NAD(P)H | /
  nitroreductase |/
         1.7.1.- | Search GenBank, 256 hits on Apr. 03, 2012
                 |\
          ExPASy | \
                 |  3NAD(P)+ + 2H2O
                 v
    4-Amino-2,6-dinitrotoluene
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
Nitroaromatic -----> Aminoaromatic (bt0080)
[Trinitrotoluene] [2,4,6-Trinitrotoluene (anaerobic)] [BBD Main Menu]

Page Author(s): Sara McFarlan
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0460.
It was generated on March 1, 2025 at 9:32:24 AM CST. 

© 2025, EAWAG.