Carbaryl, a wide-spectrum, moderately to very toxic, N-methylcarbamate insecticide, controls over 100 species of insects. Current study shows it can produce adverse effects in humans by skin contact, inhalation, or ingestion. Carbaryl can also be harmful to human organ(s). Ingestion of carbaryl affects the lungs, kidneys, and liver.
The carbaryl pathway is described by Vandana et al., (2005). Pseudomonas sp. strains C4, C5, and C6 utilize carbaryl as the sole source of carbon and energy. The metabolic pathway of carbaryl starts from 1-naphthol to 1,2-dihydroxynaphthalene and then into the napthalene pathway for degradation into intermediary metabolism.
The following is a text-format carbaryl pathway map. An organism which can initiate the pathway is given, but other organisms may also carry out later steps. Follow the links for more information on compounds or reactions. This map is also available in graphic (4k) format.
Carbaryl
Pseudomonas sp. C4, C5 and C6
|
|
| carbaryl
| hydrolase
|
v
1-Naphthol + Methylamine
| |
| |
1-naphthol | |
hydroxylase | v
| to the
v Glyphosate
1,2-Dihydroxynaphthalene Pathway
|
|
|
v
to the
Naphthalene
Pathway
Page Author(s): Junfeng Gao
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