Rule bt0439

[Pathway Prediction Engine] [All Rules List] [BBD Main Menu]
Pattern 4270
2-Phenylacyl derivative -> Catechol derivative + Acyl derivative


Aerobic Likelihood:              Unlikely

EAWAG-BBD Reaction(s):
Not found

Comments:
This rule handles the 2-phenylacyl dioxygenation pathway and includes CoA ligation to the acyl (acetyl or 2-propanyl) substituent, 1,2-dioxygenation, elimination of acyl-CoA, and formation of the catechol derivative, based on Murdoch and Hay (2005) and a review by Kagle et al. (2009).

Similarities:
bt0055: 1-carboxy-2-unsubstituted Aromatic --> Catechol derivative

Contact Us if you have any comments on rule bt0439.
[Pathway Prediction Engine] [All Rules List] [BBD Main Menu]

Page Author(s): Michael Turnbull
October 27, 2011

This is the EAWAG-BBD biotransformation rule, ruleID# bt0439.
It was generated on February 2, 2025 5:06:36 PM CST. 

© 2025, EAWAG.