From Benzo(a)pyrene-cis-7,8-dihydrodiol to cis-4-(7-Hydroxypyren-8-yl)-2-oxobut-3-enoate

Graphic of the reaction.

Medline reference
Schneider J, Grosser R, Jayasimhulu K, Xue W, Warshawsky D. Appl Environ Microbiol (1996) 62(1): 13-9.

Search Medline titles for Benzo(a)pyrene AND bacteria.
9 citations on September 05, 2012.
              Benzo(a)pyrene-cis-7,8-dihydrodiol               
                               |
                               |
  7,8-dihydroxy benzo(a)pyrene |
                   dioxygenase |
                       1.3.-.- |
                               |\
                        ExPASy | \
                               |  2H+ + 2e-
                               v
                 [7,8-Dihydroxybenzo(a)pyrene]                 
                               |
                               |  O2
                               | /
                               |/
                               |
                               |\
                               | \
                               |  H+
                               v
         cis-4-(7-Hydroxypyren-8-yl)-2-oxobut-3-enoate         
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-Dihydrodihydroxyaromatic -----> vic-Dihydroxyaromatic (bt0255)

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Page Author(s): Edward Zhang
February 12, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1138.
It was generated on October 24, 2019 12:18:20 AM CDT.

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