From 4,6-Dichloro-3-methylcatechol to 3,5-Dichloro-3-methyl-cis,cis-muconate

Graphic of the reaction.

Medline reference
Pollmann K, Kaschabek S, Wray V, Reineke W, Pieper DH. J Bacteriol (2002) 184(19): 5261-74.

Search Medline for chlorocatechol 1,2-dioxygenase.
69 citations on March 09, 2012. 
                  4,6-Dichloro-3-methylcatechol                  
                                |
                                |  O2
  4,6-dichloro-3-methylcatechol | /
                1,2-dioxygenase |/
                      1.13.11.- | Search GenBank, 214 hits on Apr. 03, 2012
                                |\
                         ExPASy | \
                                |  2H+
                                v
             3,5-Dichloro-3-methyl-cis,cis-muconate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-Dihydroxyaromatic -----> intradiol ring cleavage (bt0254)
[2,4-Dichlorotoluene] [BBD Main Menu]

Page Author(s): David Wunder
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0959.
It was generated on October 10, 2024 at 9:53:51 AM CDT. 

© 2024, EAWAG.