From 2,4-Dichlorotoluene to 4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene

Graphic of the reaction.

Medline reference
Pollmann K, Kaschabek S, Wray V, Reineke W, Pieper DH. J Bacteriol (2002) 184(19): 5261-74.

Search Medline for tetrachlorobenzene dioxygenase TecA.
5 citations on March 09, 2012.
                      2,4-Dichlorotoluene                      
                               |
                               |  NADH + H+ + O2
            tetrachlorobenzene | /
                   dioxygenase |/
                     1.14.12.- |
                               |\
                        ExPASy | \
                               |  NAD+
                               v
  4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene   
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-unsubstituted Aromatic -----> vic-Dihydrodihydroxyaromatic (bt0367)

[2,4-Dichlorotoluene] [BBD Main Menu]

Page Author(s): David Wunder
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0957.
It was generated on June 27, 2019 7:20:54 AM CDT.

© 2019, EAWAG.