From 3-Chloro-cis,cis-muconate to 4-Methylenebut-2-en-4-olide

Graphic of the reaction.

Medline reference
Helin S, Kahn PC, Guha BL, Mallows DG, Goldman A. J Mol Biol (1995) 254(5): 918-41.

Search Medline titles for muconate cycloisomerase.
13 citations on June 22, 2012.
     3-Chloro-cis,cis-muconate     
                 |
                 |
        muconate |
  cycloisomerase |
         5.5.1.1 | Search GenBank, 411 hits on Apr. 03, 2012
           Kyoto |\
          ExPASy | \
                 |  Cl- + CO2
                 v
    4-Methylenebut-2-en-4-olide    
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
3-Halo-cis,cis-muconate derivative -----> cis-4-Carboxymethylenebut-2-en-4-olide derivative (bt0206)
2- or 3- substituted Carboxylate -----> RH + CO2 (bt0051)

[2,4-Dichlorophenoxyacetic Acid] [BBD Main Menu]

Page Author(s): Eva Young
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0284.
It was generated on September 26, 2017 6:07:53 AM CDT.

© 2017, EAWAG.