From 4-Hydroxytoluene to 4-Hydroxybenzaldehyde

Graphic of the reaction.

Medline reference
McIntire W, Singer TP, Smith AJ, Mathews FS. Biochemistry (1986) 25(20): 5975-81.

Search Medline titles for p-cresol methylhydroxylase.
28 citations on June 22, 2012.
        4-Hydroxytoluene         
                |
                |  H2O + acceptor
       4-cresol | /
  dehydrogenase |/
      1.17.99.1 | Search GenBank, 84 hits on Apr. 03, 2012
          Kyoto |\
         ExPASy | \
                |  2e- + 2H+ + reduced acceptor
                v
    [4-hydroxybenzyl alcohol]    
                |
                |  H2O + acceptor
                | /
                |/
                |
                |\
                | \
                |  2e- + 2H+ + reduced acceptor
                v
      4-Hydroxybenzaldehyde      
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
aromatic Methyl -----> primary Alcohol (bt0036)
primary Alcohol -----> Aldehyde (bt0001)

[Toluene] [BBD Main Menu]

Page Author(s): Yuemo Zeng
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0272.
It was generated on September 24, 2017 3:43:19 AM CDT.

© 2017, EAWAG.