The EAWAG-BBD Benzoate (anaerobic) Pathway

• Acetoacetyl-CoA + Coenzyme A -----> Acetyl-CoA (reacID# r0201)
• Benzoate -----> Benzoyl-CoA (reacID# r0189)
• Benzoyl-CoA -----> Cyclohex-1,5-diene-1-carboxyl-CoA (reacID# r0190)
• Crotonoyl-CoA -----> (3S)-3-Hydroxybutyryl-CoA (reacID# r0200)
• Cyclohex-1,4-diene-1-carboxyl-CoA -----> Cyclohex-1,5-diene-1-carboxyl-CoA (reacID# r0507)
• Cyclohex-1,5-diene-1-carboxyl-CoA -----> 6-Hydroxycyclohex-1-ene-1-carboxyl-CoA (reacID# r0203)
• Cyclohex-1-ene-1-carboxyl-CoA -----> 2-Hydroxycyclohexane-1-carboxyl-CoA (reacID# r0191)
• Cyclohex-2,5-diene-1-carboxyl-CoA -----> Cyclohex-1,5-diene-1-carboxyl-CoA (reacID# r0506)
• 2,3-Didehydro-pimeloyl-CoA -----> 3-Hydroxypimelyl-CoA (reacID# r0195)
• 2,6-Dihydroxycyclohexane-1-carboxyl-CoA -----> 6-Oxo-2-hydroxycyclohexane-1-carboxyl-CoA (reacID# r0205)
• Glutaconyl-CoA -----> Crotonoyl-CoA (reacID# r0199)
• Glutaryl-CoA -----> Glutaconyl-CoA (reacID# r0198)
• (3S)-3-Hydroxybutyryl-CoA -----> Acetoacetyl-CoA (reacID# r0202)
• 6-Hydroxycyclohex-1-ene-1-carboxyl-CoA -----> 2,6-Dihydroxycyclohexane-1-carboxyl-CoA (reacID# r0204)
• 2-Hydroxycyclohexane-1-carboxyl-CoA -----> 2-Ketocyclohexane-1-carboxyl-CoA (reacID# r0192)
• 3-Hydroxypimelyl-CoA -----> 3-Ketopimelyl-CoA (reacID# r0196)
• 2-Ketocyclohexane-1-carboxyl-CoA -----> Pimeloyl-CoA (reacID# r0193)
• 3-Ketopimelyl-CoA -----> Glutaryl-CoA + Acetyl-CoA (reacID# r0197)
• 6-Oxo-2-hydroxycyclohexane-1-carboxyl-CoA -----> 3-Hydroxypimelyl-CoA (reacID# r0206)
• Pimeloyl-CoA -----> 2,3-Didehydro-pimeloyl-CoA (reacID# r0194)
• Terephthalate -----> Benzoate (reacID# r0321)

• Acetoacetyl-CoA [1420-36-6] (compID# c0229)
• Acetyl-CoA [72-89-9] (compID# c0031)
• Benzoate [65-85-0] (compID# c0121)
• Benzoyl-CoA [6756-74-7] (compID# c0119)
• Coenzyme A [85-61-0] (compID# c0919)
• Crotonoyl-CoA [102680-35-3] (compID# c0032)
• Cyclohex-1,4-diene-1-carboxyl-CoA (compID# c0214)
• Cyclohex-1,5-diene-1-carboxyl-CoA (compID# c0212)
• Cyclohex-1-ene-1-carboxyl-CoA (compID# c0215)
• Cyclohex-2,5-diene-1-carboxyl-CoA (compID# c0213)
• 2,3-Didehydro-pimeloyl-CoA (compID# c0219)
• 2,6-Dihydroxycyclohexane-1-carboxyl-CoA (compID# c0231)
• Glutaconyl-CoA (compID# c0227)
• Glutaryl-CoA [103192-48-9] (compID# c0222)
• (3S)-3-Hydroxybutyryl-CoA (compID# c0030)
• 6-Hydroxycyclohex-1-ene-1-carboxyl-CoA (compID# c0230)
• 2-Hydroxycyclohexane-1-carboxyl-CoA (compID# c0216)
• 3-Hydroxypimelyl-CoA (compID# c0220)
• 2-Ketocyclohexane-1-carboxyl-CoA (compID# c0217)
• 3-Ketopimelyl-CoA (compID# c0221)
• 6-Oxo-2-hydroxycyclohexane-1-carboxyl-CoA (compID# c0232)
• Pimeloyl-CoA [18907-20-5] (compID# c0218)
• Terephthalate [100-21-0] (compID# c0184)

• EC 1.1.-.- 2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase (enzymeID# e0186)
• EC 1.1.-.- 2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase (enzymeID# e0177)
• EC 1.1.1.36 acetoacetyl-CoA reductase (enzymeID# e0005)
• EC 1.1.1.259 3-hydroxypimeloyl-CoA dehydrogenase (enzymeID# e0181)
• EC 1.3.1.62 pimeloyl-CoA dehydrogenase (enzymeID# e0179)
• EC 1.3.7.8 benzoyl-CoA reductase (enzymeID# e0176)
• EC 1.3.8.6 glutaryl-CoA dehydrogenase (enzymeID# e0123)
• EC 2.3.1.- 3-ketopimelyl-CoA thiolase (enzymeID# e0182)
• EC 2.3.1.9 acetoacetyl-CoA thiolase (enzymeID# e0144)
• EC 3.7.1.- 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA hydrolase (enzymeID# e0187)
• EC 3.7.1.- 2-ketocyclohexane-1-carboxyl-CoA hydrolase (enzymeID# e0178)
• EC 4.1.1.- terephthalate decarboxylase (enzymeID# e0621)
• EC 4.1.1.70 glutaconyl-CoA decarboxylase (enzymeID# e0136)
• EC 4.2.1.- 6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase (enzymeID# e0185)
• EC 4.2.1.- cyclohex-1-ene-1-carboxyl-CoA hydratase (enzymeID# e0175)
• EC 4.2.1.17 enoyl-CoA hydratase (enzymeID# e0014)
• EC 4.2.1.100 dienoyl-CoA hydratase (enzymeID# e0184)
• EC 6.2.1.25 benzoate-CoA ligase (enzymeID# e0131)

Page Author(s): Alfred Spormann, Dong Jun Oh and Meaghan Fitzgerald
December 15, 1997 4:34:50 PM CST Contact Us

This is the EAWAG-BBD compounds and reactions page for the Benzoate (anaerobic) Pathway.
It was generated on April 16, 2024 at 4:18:16 PM CDT.

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